Cerebrovascular autoregulation in hypoxia: quantitative insights from arterial spin labeling

Hypoxia, defined as an insufficient oxygen supply relative to metabolic demand, induces a cascade of cerebrovascular and metabolic responses aimed at preserving cerebral homeostasis. These responses vary depending on the temporal profile of exposure, with acute (e.g., hypoxic–ischemic encephalopathy, acute high-altitude exposure) versus chronic (e.g., obstructive sleep apnea, long-term altitude residence) conditions, and may range […]